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Exendin-4 treatment for 8–12 weeks also reduced atherosclerosis (7, 8) and plaque macrophages (8) in Ldlr –/– mice on a high-cholesterol diet (HCD) (6)
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Weight Loss: The average percent weight loss from patients’ starting weight after these 17 months at the maintenance dose was: -15% weight loss from baseline body weight at 68 weeks at the 2.4mg dose -In a two year follow up study, those who continued to take semaglutide at the 2.4mg dose were able to maintain an average of 15.2% of their initial weight
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